|
| Status |
Public on Apr 07, 2020 |
| Title |
CELL CONTRACTILITY AND AN ACTIN GRADIENT DRIVE POLAR ALIGNMENT OF FIBROBLASTS IN CONSTRAINED GEOMETRIES |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
When REF 2c cells were placed on circular micro-contact printed patterns, the boundary cells radially aligned over a period of 48 h. Video tracking of specific boundary and inner cells showed that this phenomenon was not caused by cells migrating towards or away from the periphery. Cell contractility, intercellular junctions, and cell-cell adhesion are required for radial alignment.
|
| |
|
| Overall design |
Examination the gene expression differences between 2 different REF subclones.
|
| |
|
| Contributor(s) |
Xie T, St. Pierre SR, Sun Y |
| Citation(s) |
34542405 |
| Submission date |
Apr 06, 2020 |
| Last update date |
Sep 24, 2021 |
| Contact name |
Tianfa Xie |
| Organization name |
University of Massachusetts Amherst
|
| Department |
Mechanical and Industrial Engineering
|
| Lab |
Yubing Sun Lab
|
| Street address |
240 Thatcher Way
|
| City |
Amherst |
| State/province |
Massachusetts |
| ZIP/Postal code |
01003 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
|
| Samples (2) |
|
| Relations |
| BioProject |
PRJNA623348 |
| SRA |
SRP255393 |
