|
| Status |
Public on Jul 14, 2020 |
| Title |
ChIP-Seq for HOXB13 in LNCaP cell line with GSK treatment and VEH control |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We show in prostate cancer cells that LSD1 co-localizes with FOXA1 and active enhancer markers, and that LSD1 inhibition globally disrupts FOXA1 chromatin binding.
|
| |
|
| Overall design |
ChIP-Seq of HOXB13 was performed in LNCaP cells treated with vehicle or GSK2879552
|
| Web link |
https://doi.org/10.1038/s41588-020-0681-7
|
| |
|
| Contributor(s) |
Gao S, Han D, Chen S, He HH, Cai C |
| Citation(s) |
32868907 |
| |
| Submission date |
Apr 20, 2020 |
| Last update date |
Oct 13, 2020 |
| Contact name |
Changmeng Cai |
| E-mail(s) |
changmeng.cai@umb.edu
|
| Organization name |
University of Massachusetts Boston
|
| Street address |
100 William T. Morrissey Blvd.
|
| City |
Boston |
| State/province |
Massachusetts |
| ZIP/Postal code |
02125 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE149007 |
Lineage-specific chromatin binding of FOXA1 is regulated by LSD1-mediated demethylation |
|
| Relations |
| BioProject |
PRJNA627124 |
| SRA |
SRP257689 |
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