|
Status |
Public on Mar 16, 2021 |
Title |
Single cell RNA sequencing of large and small airway surface epithelium in newborn cystic fibrosis (CF) and non-CF pigs |
Organism |
Sus scrofa |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
The goal of this study was to compare cell composition and gene expression patterns for different cell types in large and small airways of CFTR+/+ (non-CF) and CFTR-/- (CF) pigs.
|
|
|
Overall design |
Tissue samples from trachea and small airways (< 2 mm) were collected from newborn pigs, prepared for single cell sequencing via 10X Genomics Chromium controller, and sequenced on Illumina HiSeq4000
|
|
|
Contributor(s) |
Pezzulo AA, Thurman AL, Yu W, Zabner J, Welsh MJ |
Citation(s) |
33970215, 36108628 |
|
Submission date |
May 10, 2020 |
Last update date |
Jan 06, 2023 |
Contact name |
Alejandro A. Pezzulo |
E-mail(s) |
alejandro-pezzulo@uiowa.edu
|
Organization name |
Universty of Iowa
|
Department |
Department of Internal Medicine
|
Lab |
Pezzulo Lab
|
Street address |
6316 Pappajohn Biomedical Discovery Building
|
City |
Iowa City |
State/province |
Iowa |
ZIP/Postal code |
52242 |
Country |
USA |
|
|
Platforms (1) |
GPL22475 |
Illumina HiSeq 4000 (Sus scrofa) |
|
Samples (19)
|
|
Relations |
BioProject |
PRJNA631526 |
SRA |
SRP261147 |