|
| Status |
Public on Jul 30, 2020 |
| Title |
Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination |
| Organism |
Mus musculus |
| Experiment type |
Other
|
| Summary |
We report here high-throughput sequencing analyses of class switch recombination junctions in Lsh deficient B cells with reduced capacity of class switch recombination compared to control B cells.
|
| |
|
| Overall design |
Examination of genomic localization of junctions and junction patterns among purified B cells derived from conditional Lsh-/- vav (KO) or control (CTRL) mice
|
| |
|
| Contributor(s) |
Muegge K, He Y, Ren J, Finney R |
| Citation(s) |
32727902 |
| |
| Submission date |
May 12, 2020 |
| Last update date |
Jul 30, 2020 |
| Contact name |
Scott Durum |
| E-mail(s) |
durums@mail.nih.gov
|
| Phone |
3018461545
|
| Organization name |
National Cancer Institute
|
| Department |
CCR
|
| Lab |
Cancer Innovation Labratory
|
| Street address |
Building 560, Room 31-71
|
| City |
Frederick |
| State/province |
MD |
| ZIP/Postal code |
21702-1201 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (13)
|
|
| Relations |
| BioProject |
PRJNA632014 |
| SRA |
SRP261327 |
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