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Status |
Public on May 14, 2020 |
Title |
Episodic vestibular syndrome with hyperventilation-induced downbeat nystagmus |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
The aim of this study was to investigate the clinical characteristics and underlying pathogenesis of episodic vestibular syndrome (EVS) with hyperventilation-induced downbeat nystagmus (HV-DBN).
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Overall design |
Total RNAs were extracted from peripheral blood mononuclear cells of 7 EVS with HV-DBN patients and 7 normal controls. Using the Affymetrix Human Clariom S Assay, the differentially expressed genes (DEGs) between AUV and normal control samples were screened by the cut-off criteria (|fold changes| > 1.5 and p-value < 0.05). Functional enrichment analysis for DEGs was performed using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, and the protein-protein interaction (PPI) network was constructed using the STRING database.
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Contributor(s) |
Oh E, Choi J |
Citation missing |
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Submission date |
May 13, 2020 |
Last update date |
May 16, 2020 |
Contact name |
Jae-Hwan Choi |
E-mail(s) |
rachelbolan@hanmail.net
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Organization name |
Pusan National University Yangsan Hospital
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Department |
Neurology
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Street address |
Kumo-ro 20, Beomo-ri, Mulgum-eup
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City |
Yangsan |
ZIP/Postal code |
50612 |
Country |
South Korea |
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Platforms (1) |
GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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Samples (14)
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Relations |
BioProject |
PRJNA632479 |