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Status |
Public on Apr 14, 2021 |
Title |
ChIP-seq analysis of MED1 and FOSL1 in SCC1 cells after depletion of FOSL1 |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
To explore genome-wide alteration MED1 and FOSL1 after depletion of FOSL1, we performed chromatin immunoprecipitation sequencing (ChIP-seq) of SCC1 cells to examine genome-wide recruitment of MED1 and FOSL1 following FOSL1 knockdown. Depletion of FOSL1 led to dramatically loss of the recruitment of MED1 and FOSL1 at a cohort of key oncogenes associate with tumorigenesis and metastasis.
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Overall design |
Examination of ChIP-seq of HNSCC cells treated with FOSL1 siRNA.
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Contributor(s) |
Li J |
Citation missing |
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Submission date |
May 25, 2020 |
Last update date |
Apr 17, 2021 |
Contact name |
Jiong Li |
E-mail(s) |
jli29@vcu.edu
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Phone |
3105617186
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Organization name |
VCU
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Street address |
800 E Leigh Street, suite 212
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City |
Richmond |
State/province |
Virginia |
ZIP/Postal code |
23298 |
Country |
USA |
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Platforms (1) |
GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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Samples (4)
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Relations |
BioProject |
PRJNA634845 |
SRA |
SRP263455 |