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Series GSE15119 Query DataSets for GSE15119
Status Public on Mar 06, 2009
Title Mammary tumors in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5
Organism Mus musculus
Experiment type Expression profiling by array
Summary Stat5 is a latent transcription factor that regulates essential growth and survival functions in normal cells. Constitutive activity of Stat5 and the involvement of its C-terminally truncated variant have been implicated in blood cell malignancies and mammary or breast cancer.
To distinguish the individual contributions of the Stat5 variants to mammary tumorigenesis, global gene-expression profiling was performed on transgenic STAT5-induced tumors.
 
Overall design Mammary tumors derived from transgenic mice carrying one of two Stat5 variants were collected for RNA extraction and hybridization on Affymetrix GeneChip® Mouse Genome 430A 2.0 array.
 
Contributor(s) Eilon T, Barash I
Citation(s) 20717961, 19450255
Submission date Mar 05, 2009
Last update date Mar 25, 2020
Contact name Tali Eilon
Organization name The Volcani Center
Street address Rehovot
City Rehovot
ZIP/Postal code 17000
Country Israel
 
Platforms (1)
GPL8321 [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
Samples (16)
GSM377882 Mammary gland_1
GSM377883 Mammary gland_4
GSM377884 Mammary gland_6
Relations
BioProject PRJNA114871

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE15119_RAW.tar 32.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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