|
| Status |
Public on Nov 27, 2020 |
| Title |
Intrauterine inflammation-induced transcriptome changes in the mouse placenta |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Placental insufficiency is implicated in the intrauterine infection-associated spontaneous preterm birth. Using a mouse model of LPS-induced intrauterine inflammation that leads to preterm delivery, RNA-seq study was performed in the placenta at gestational day 17 to assess the transcriptome changes.
|
| |
|
| Overall design |
Examinatin of transcriptomes in 2 experimental conditions (LPS and control)
|
| |
|
| Contributor(s) |
Lien Y, Simmons RA, Zhang Z, Barila G, Green-Brown A, Elovitz MA |
| Citation(s) |
33250783 |
|
https://doi.org/10.3389/fphys.2020.592689
|
| |
| Submission date |
Jun 03, 2020 |
| Last update date |
Dec 01, 2020 |
| Contact name |
Zhe Zhang |
| E-mail(s) |
zhezhang@upenn.edu
|
| Organization name |
University of Pennsylvania
|
| Street address |
Translational Research Lab
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA637059 |
| SRA |
SRP265823 |
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