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Status |
Public on Sep 26, 2022 |
Title |
RNAseq of livers from WT mice or livers with Rbfox2 knockout fed CD |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Rbfox2 is required for maintaining hepatic metabolic homeostasis, here we carry out RNAseq to of WT and aged matched littermate Rbfox2 knockout mice under high fructose in order to determine changes in alternative splicing and mRNA expression caused by knockout of this splicing factor in this metabolic environment.
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Overall design |
RNAseq of liver tissue from control diet and high fat diet (60% cal. from fat) mice harvested under fasted (16h) status
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Contributor(s) |
Vernia S, Wang Y, Paterson HA |
Citation missing |
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Submission date |
Jun 03, 2020 |
Last update date |
Sep 26, 2022 |
Contact name |
LMS Bioinformatics Core |
E-mail(s) |
bioinformatics@lms.mrc.ac.uk
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Organization name |
MRC London Institute of Medical Sciences
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Department |
Bioinformatics Core
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Street address |
Hammersmith Hospital Campus, Du Cane Road
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City |
London |
ZIP/Postal code |
W12 0NN |
Country |
United Kingdom |
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Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (8)
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GSM4589737 |
Control diet wild-type liver_sample4 |
GSM4589738 |
Control diet Rbfox2 knockout liver_sample1 |
GSM4589739 |
Control diet Rbfox2 knockout liver_sample2 |
GSM4589740 |
Control diet Rbfox2 knockout liver_sample3 |
GSM4589741 |
Control diet Rbfox2 knockout liver_sample4 |
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This SubSeries is part of SuperSeries: |
GSE151753 |
Characterization of the role of RBFOX2 in the liver |
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Relations |
BioProject |
PRJNA637086 |
SRA |
SRP265846 |