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| Status |
Public on Jun 05, 2020 |
| Title |
Transcriptomic analysis of adipose and muscle of dairy calves supplemented with 5-hydroxytryptophan |
| Organism |
Bos taurus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Serotonin is a monoamine that regulates processes such as energy balance and immune function. Manipulating this pathway in growing dairy calves could promote growth and development by modulating functions and signaling pathways within key organs. In this study, we characterized the adipose and muscle transcriptome of pre-weaned calves with increased serotonin bioavailability through the elucidation of differentially expressed genes.
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| Overall design |
Holstein bull calves (21d old) were fed milk replacer (8 L/d) supplemented with saline (CON, n=4) or 5-hydroxytryptophan (5HTP, n=4) for 10 d. Calves were euthanized on d 10 to harvest adipose and muscle tissue for RNA-Sequencing.
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| Contributor(s) |
Laporta J, Peñagaicano F |
| Citation(s) |
33958639 |
| Submission date |
Jun 04, 2020 |
| Last update date |
May 20, 2021 |
| Contact name |
Francisco Peñagaricano |
| E-mail(s) |
fpenagarican@wisc.edu
|
| Organization name |
University of Wisconsin-Madison
|
| Department |
Animal and Dairy Sciences
|
| Street address |
1675 Observatory Drive
|
| City |
Madison |
| State/province |
Wisconsin |
| ZIP/Postal code |
53706 |
| Country |
USA |
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| Platforms (1) |
| GPL26012 |
Illumina NovaSeq 6000 (Bos taurus) |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA637233 |
| SRA |
SRP265919 |
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