|
| Status |
Public on Sep 17, 2020 |
| Title |
LCM-Seq analysis of microscopically defined human embryo HSC microenvironment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This dataset contains RNA-Seq data for cells within spatially defined subdomains of the human embryo dorsal aorta, subdissected from tissue sections using laser capture microdissection. This dataset explores dorsal-ventral polarisation across the dorsal aorta, the site of hematopoietic stem cell emergence.
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| |
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| Overall design |
In total 30 samples (subdomains) from 6 human embryos are analysed. This includes 6 subdomains (V_Inner, D_Inner, V_Mid, D_Mid, V_Outer, D_Outer) from 3 CS16 embryos and 4 subdomains ([V], [VL], [DL], [D]) from 3 CS17 embryos.
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| |
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| Contributor(s) |
Crosse EI, Medvinsky A |
| Citation(s) |
32946788 |
| |
| Submission date |
Jun 05, 2020 |
| Last update date |
Dec 01, 2020 |
| Contact name |
Edie Crosse |
| E-mail(s) |
edie.crosse@outlook.com
|
| Organization name |
University of Edinburgh
|
| Department |
Centre for Regenerative Medicine
|
| Street address |
5 Little France Road
|
| City |
Edinburgh |
| ZIP/Postal code |
EH16 4UU |
| Country |
United Kingdom |
| |
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| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (30)
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| This SubSeries is part of SuperSeries: |
| GSE151877 |
Parallel spatial transcriptomics, single-cell and bulk RNA-Seq analysis of the human embryonic HSC niche, the dorsal aorta |
|
| Relations |
| BioProject |
PRJNA637577 |
| SRA |
SRP266127 |
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