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| Status |
Public on Jul 01, 2021 |
| Title |
Effects of cannabidiol on the inflammation-stimulated keratinocytes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Cannabidiol (CBD) oral spray on murine oral ulcer significantly inhibited inflammation, relieved pain and accelerated healing process. To gain insight into transcriptional regulation of CBD on cells related to healing progress of oral ulcer, we performed RNA-Seq on the immortalized human oral keratinocyte HOK-16B cell lines stimulated with LPS and ATP, after 10μM CBD or vehicle excipient pretreatment.
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| |
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| Overall design |
Comparison of gene expression between inflammation-stimulated HOK-16B cell lines pretreated with CBD or vehicle
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| |
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| Contributor(s) |
Qi X, Yuan Q |
| Citation(s) |
34269108 |
| |
| Submission date |
Jun 09, 2020 |
| Last update date |
Sep 30, 2021 |
| Contact name |
Quan Yuan |
| E-mail(s) |
yuanquan@scu.edu.cn
|
| Organization name |
West China Hospital of Stomatology, Sichuan University
|
| Lab |
State Key laboratory of Oral Diseases
|
| Street address |
14 Third section, Renmin Nan Road
|
| City |
Chengdu |
| State/province |
Sichuan |
| ZIP/Postal code |
610041 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA638292 |
| SRA |
SRP266587 |
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