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Series GSE153089 Query DataSets for GSE153089
Status Public on Nov 20, 2020
Title A microRNA cluster in the DLK1-DIO3 imprinted region on chromosome 14q32.2 in hepatoblastoma
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Using array-based expression analysis on formalin-fixed paraffin-embedded tissues, we aimed to identify miRNA signatures that can discriminate between lung metastatic tumors, primary tumors (fetal and embryonal subtypes) and nontumorous surrounding livers.
A large cluster of microRNAs and snoRNAs located within the 14q32.2 DLK1-DIO3 region showed a strikingly upregulated expression pattern in HB tumors, especially metastatic tumors, compared to normal liver tissues.
 
Overall design Here we examined microRNAs and snoRNAs profiles related to different type of hepatoblastoma tumor cells, using array-based expression analysis.
 
Contributor(s) Honda S, Chatterjee A, Leichter AL, Eccles MR
Citation(s) 33282720
Submission date Jun 23, 2020
Last update date Dec 08, 2020
Contact name Shohei Honda
E-mail(s) s-honda@med.hokudai.ac.jp
Phone 0117065927
Organization name Hokkaido University Hospital
Department Department of Gastroenterological surgery I
Street address Kita-14,Nishi-5
City Sapporo
ZIP/Postal code 060-8648
Country Japan
 
Platforms (1)
GPL21572 [miRNA-4] Affymetrix Multispecies miRNA-4 Array [ProbeSet ID version]
Samples (44)
GSM4633961 Case 6_H16N
GSM4633962 Case 6_H16F
GSM4633963 Case 10_2M
Relations
BioProject PRJNA641410

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE153089_RAW.tar 35.8 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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