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| Status |
Public on Apr 19, 2021 |
| Title |
NusG is an intrinsic transcription termination factor that stimulates motility and cooperatively coordinates global gene expression with NusA |
| Organism |
Bacillus subtilis |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In this work we conducted Term-seq on Wild Type, NusA depletion, nusG deletion, and NusA depletion nusG deletion strains of B. subtilis. Using this approach, we found that NusG is an intrinsic termination factor that works single and cooperatively with NusA.
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| Overall design |
Term-seq on Wild Type, NusA depletion, nusG deletion, and NusA depletion nusG deletion strains of B. subtilis followed by in vitro and physiological follow-up
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| |
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| Contributor(s) |
Mandell ZF, Oshiro RT, Yakhnin AV, Kashlev M, Kearns DB, Babitzke P |
| Citation(s) |
33835023, 35699226 |
| |
| Submission date |
Jul 15, 2020 |
| Last update date |
Jul 07, 2022 |
| Contact name |
Paul Babitzke |
| E-mail(s) |
pxb28@psu.edu
|
| Organization name |
Pennsylvania State University
|
| Street address |
203 Althouse Laboratory
|
| City |
State College |
| State/province |
PA |
| ZIP/Postal code |
16802 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL24109 |
Illumina NextSeq 500 (Bacillus subtilis) |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA646522 |
| SRA |
SRP272134 |
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