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| Status |
Public on Jan 26, 2021 |
| Title |
Epigenetic reprogramming events rewire transcription during the alternation of generations in Arabidopsis [ATAC-Seq] |
| Organism |
Arabidopsis thaliana |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Alternation between morphologically distinct haploid and diploid life forms is a defining feature of most plant and algal life cycles, yet the underlying molecular mechanisms that govern these transitions remain unclear. Here, we explore the dynamic relationship between chromatin accessibility and epigenetic modifications during life form transitions in Arabidopsis. The diploid-to-haploid life form transition is governed by the loss of H3K9me2 and DNA demethylation of transposon-associated cis-regulatory elements, which is associated with dramatic changes in chromatin accessibility and transcriptional reprogramming. In contrast, the global loss of H3K27me3 in the haploid form shapes a chromatin accessibility landscape that is poised to re-initiate the transition back to diploid life after fertilization. These distinct epigenetic reprogramming events rewire transcription through major reorganization of the regulatory epigenome to guide the alternation of generations in flowering plants.
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| |
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| Overall design |
Genome-wide maps of chromatin accessilbity in developing Arabidopsis pollen
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| |
|
| Contributor(s) |
Borg M |
| Citation(s) |
33491647 |
| |
| Submission date |
Jul 29, 2020 |
| Last update date |
Jun 12, 2024 |
| Contact name |
Michael Borg |
| E-mail(s) |
borgmichael@gmail.com
|
| Organization name |
Gregor Mendel Institute
|
| Lab |
Berger Lab
|
| Street address |
Dr. Bohr-Gasse 3
|
| City |
Vienna |
| ZIP/Postal code |
1030 |
| Country |
Austria |
| |
|
| Platforms (1) |
| GPL17639 |
Illumina HiSeq 2500 (Arabidopsis thaliana) |
|
| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE155369 |
Epigenetic reprogramming rewires transcription during the alternation of generations in Arabidopsis |
|
| Relations |
| BioProject |
PRJNA649438 |
| SRA |
SRP274096 |
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