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| Status |
Public on Aug 01, 2021 |
| Title |
Transcriptome Profiling sequencing analysis of feline ovarian granulosa cell treated with Atractylenolide Ⅰ |
| Organism |
Felis catus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Through the application of a transcriptome profiling strategy, we were able to ascertain the differentially expressed genes and complicated pathways involved in the interactions between Atractylenolide-I and feline ovarian granulosa cells. Based on the results of our transcriptome profiling study, we found the highest number of DEGs participated in cholesterol metabolism pathways, the activation of which might be a major factor underlying Atractylenolide I promote the luteinization of the feline ovarian granulosa cells.
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| Overall design |
Divided into treatment group and control group,Three biological replicates were designed for the treatment and control experiments
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| Contributor(s) |
Guo Y, Liu C, Cao J |
| Citation missing |
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| |
| Submission date |
Aug 06, 2020 |
| Last update date |
Aug 01, 2021 |
| Contact name |
Yuli Guo |
| E-mail(s) |
yuliguo@emails.imau.edu.cn
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| Phone |
15849123015
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| Organization name |
Inner Mongolia Agricultural University
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| Lab |
Key Laboratory of Clinical Diagnosis and Treatment Techniques for Animal Disease, College of Veterinary Medicine
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| Street address |
Zhaowuda Road
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| City |
Hohhot |
| ZIP/Postal code |
010000 |
| Country |
China |
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| Platforms (1) |
| GPL23056 |
Illumina HiSeq 4000 (Felis catus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA655621 |
| SRA |
SRP276351 |
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