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Series GSE156621 Query DataSets for GSE156621
Status Public on Sep 30, 2021
Title Transcriptomic analysis of MSTO-211H cell variant resistant to CAR T cell therapy
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We developed MPM cells from pleural tumors that had relapsed after treatment with M28z CAR T cells
 
Overall design We implanted MSTO-211H in the pleura of NSG mice and after 2 weeks we treated mice with CAR T cells. Tumor from mice that relapsed ( 3 mice) were isolated and cells culture in vitro. We generated 3 cell variants from relapsed tumors
 
Contributor(s) Lopez-Lago MA, Adusumilli P
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Submission date Aug 21, 2020
Last update date Sep 30, 2021
Contact name Miguel A Lopez-Lago
E-mail(s) lopez7@mskcc.org
Organization name Memorial Sloan-kettering cancer center
Department Surgery
Lab Adusumilli lab
Street address 1275 york avenue
City New york
State/province NY
ZIP/Postal code 10065
Country USA
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (5)
GSM4735047 ML5
GSM4735048 ML6
GSM4735049 ML7
Relations
BioProject PRJNA658533
SRA SRP278378

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE156621_counts_scaled_DESeq.txt.gz 1.3 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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