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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 24, 2020 |
| Title |
Single cell RNA-sequencing reveals cellular heterogeneity and trajectories of lineage specification |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The coordinated spatial and temporal regulation of gene expression in the murine hindlimb determines the identity of mesenchymal progenitors and the development of diversity of musculoskeletal tissues they form. Hindlimb development has historically been studied with lineage tracing of individual genes selected a priori, or at the bulk tissue level, which does not allow for the determination of single cell transcriptional programs yielding mature cell types and tissues. To identify the cellular trajectories of lineage specification during limb bud development, we used single cell mRNA sequencing (scRNA-seq) to profile the developing murine hindlimb.
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| Overall design |
one sample from murine embryonic hindlimb tissue
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| Contributor(s) |
Kelly NH, Huynh NP |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 23, 2020 |
| Last update date |
Aug 29, 2024 |
| Contact name |
l y |
| E-mail(s) |
yao.lu@oebiotech.com
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| Organization name |
OE
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| Street address |
No.138 Xinjun Ring Road, Minhang District
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| City |
Shanghai |
| ZIP/Postal code |
201114 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (1) |
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| Relations |
| BioProject |
PRJNA658794 |
| SRA |
SRP278519 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE156700_RAW.tar |
210.0 Kb |
(http)(custom) |
TAR (of CSV, MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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