|
| Status |
Public on May 23, 2021 |
| Title |
scRNAseq of TAZ-CAMTA1 expressing endothelial cells in vivo |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
TAZ-CAMTA1 is a defining genetic aberration in the vascular cancer epithelioid hemangioendothelioma. We generated a novel transgenic mouse that expresses TAZ-CAMTA1 in endothelial cells. These mice develop vascular tumors in the lung and die by average on day 40. We isolated GFP + endothelial cells from three five-week old TRE-TAZ-CAMTA1;Cdh5-tTA;TRE-GFP mice and subjected these endothelial cells to scRNA-seq via the 10X genomics platform
|
| |
|
| Overall design |
scRNA seq of GFP+ cells from 5 week-old TRE-GFP;TRE-TAZ-CAMTA1;Cdh5-tTA mice
|
| |
|
| Contributor(s) |
Driskill J, Pan D |
| Citation(s) |
33766984 |
| Submission date |
Aug 24, 2020 |
| Last update date |
May 23, 2021 |
| Contact name |
Jordan Driskill |
| Organization name |
UT Southwestern
|
| Department |
Physiology
|
| Lab |
Duojia Pan
|
| Street address |
5323 Harry Hines Blvd
|
| City |
Dallas |
| State/province |
TX |
| ZIP/Postal code |
75219 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (1) |
|
| Relations |
| BioProject |
PRJNA659048 |
| SRA |
SRP278674 |
