|
Status |
Public on Oct 26, 2020 |
Title |
Gene expression of UC organoids and UC model organoids (long-term inflammation model) derived from human colonic organoids |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
Gene expression changes of human colon orgnaoids by 60weeks of inflammatory stimulation in vitro (long-term inflammed organoids) and after 10weeks from the removal of stimulation (inflammation-removed organoids). GSEA analysis was performed about RNA1-9 (Organoids #1). For the reproducibility of the analysis, GSEA was performed in triplicate. The key molecule for long-term inflammation was extracted from RNA10-12 (Organoids #2). The comparison of gene expression of organoids derived from normal(RNA1-3) and UC mucosa(RNA13-15). For the reproducibility, the analysis was performed in triplicate.
|
|
|
Overall design |
Long-term inflamed organoids vs normal organoids / Inflammation removed organoids vs normal organoids / UC orgnaoids vs normal organoids
|
|
|
Contributor(s) |
Tsuchiya K, Watanabe S |
Citation(s) |
33596306 |
|
Submission date |
Aug 24, 2020 |
Last update date |
Oct 02, 2021 |
Contact name |
Sho Watanabe |
E-mail(s) |
swatgast@tmd.ac.jp
|
Organization name |
Tokyo medical and dental university
|
Department |
gastroenterology
|
Street address |
1-5-45
|
City |
yushima bunnkyoku Tokyo |
ZIP/Postal code |
113-8510 |
Country |
Japan |
|
|
Platforms (1) |
GPL20844 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Feature Number Version] |
|
Samples (15)
|
|
Relations |
BioProject |
PRJNA659053 |