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| Status |
Public on Jun 23, 2021 |
| Title |
lncRNA Mitochondrial oxygen responsive transcript 1 (MTORT1) downstream gene microarray |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Long non-coding RNAs (lncRNAs) have been regarded to participate in multiple genetic pathways in cancer. Also, mitochondria-associated lncRNAs have been discovered to module mitochondrial function and metabolism. Previously, our lab identified oxygen responsive lncRNAs in breast cancer MCF-7 cells under normoxic, hypoxic and re-oxygenated conditions by using next generation sequencing technology. Among them, a novel mitochondrial lncRNA Mitochondrial Oxygen Responsive Transcript 1 (MTORT1) was chosen for further investigation. Therefore, the purpose of this study was to investigate the characterizations, function roles, and mechanisms of MTORT1 in breast cancer cells.
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| Overall design |
Total RNA obtained from MCF-7 cells transfected with siRNA against MTORT1 for 48 hours compared to MCF-7 cells transfected with control siRNA
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| Contributor(s) |
Lai L, Cheng Y |
| Citation(s) |
34141617 |
| Submission date |
Aug 28, 2020 |
| Last update date |
Jun 23, 2021 |
| Contact name |
Liang-Chuan Lai |
| E-mail(s) |
llai@ntu.edu.tw
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| Phone |
886-2-23123456
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| Organization name |
National Taiwan University
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| Department |
Physiology
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| Street address |
1 Jen-Ai Road, Sec 1
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| City |
Taipei |
| State/province |
Taiwan |
| ZIP/Postal code |
10051 |
| Country |
Taiwan |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA659997 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE157060_RAW.tar |
26.2 Mb |
(http)(custom) |
TAR |
| GSE157060_non-normalized_data.txt.gz |
1.1 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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