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Series GSE157433 Query DataSets for GSE157433
Status Public on Sep 04, 2020
Title RNA-seq of Runx3 cKO SFZ/DZ chondrocytes.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: To demonstrate Runx3's association with organizing the extracellular matrix in SFZ/DZ chondrocytes.
Method: RNA samples were collected from SFZ/DZ chondrocytes of 5-day-old Col2a1-Cre;Runx3fl/fl and Runx3fl/fl mice.
Results: 18 genes were up- or down-regulated by more than 2-fold in the Runx3 knockout in SFZ.
Conclusions: However, genes organizing the extracellular matrix were down-regulated in Runx3 cKO DZ chondrocytes.
 
Overall design SFZ chondrocytes mRNA profiles of 5-day old Cntl and Runx3 cKO mice.
 
Contributor(s) Nagata K, Saito T
Citation(s) 36261443
Submission date Sep 03, 2020
Last update date Oct 31, 2022
Contact name Kosei Nagata
E-mail(s) knagata-tky@umin.ac.jp
Organization name the University of Tokyo
Department Graduate School of Medicine
Lab Sensory and Motor System Medicine
Street address Hongo7-3-1
City Bunkyo-ku
State/province Tokyo
ZIP/Postal code 113-8655
Country Japan
 
Platforms (1)
GPL23479 BGISEQ-500 (Mus musculus)
Samples (12)
GSM4764831 Cntl_SFZ1
GSM4764832 Cntl_SFZ2
GSM4764833 Cntl_SFZ3
Relations
BioProject PRJNA661298
SRA SRP279990

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE157433_Runx3_TMM.txt.gz 3.0 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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