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| Status |
Public on Sep 04, 2021 |
| Title |
Blood transcriptomics for diagnosis, risk, and treatment monitoring in tuberculosis reveal the evolution and resolution of TB disease: Does one signature capture all? |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Characterization of Tuberculosis (TB) progression, diagnosis and treatment response with blood transcriptional RNA-seq analyses. Focus and underlying host immunological response and identification of new signatures for TB early diagnosis and treatment monitoring response.
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| |
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| Overall design |
Blood transcriptomics RNA-seq dataset that includes blood RNA samples collected from TB progressors at different time points before they progress to active TB disease and at time of diagnosis before anti-TB treatment (ATT), and also samples from active TB patients from diagnosis before any anti-TB treatmentATT and followed during treatment at regular time points up to one year after treatment initiation.
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| |
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| Contributor(s) |
Tabone O, O'Garra A |
| Citation(s) |
34491266 |
| |
| Submission date |
Sep 08, 2020 |
| Last update date |
Nov 26, 2021 |
| Contact name |
Anne OGarra |
| E-mail(s) |
Anne.OGarra@crick.ac.uk
|
| Organization name |
Francis Crick Insititue
|
| Lab |
IMMUNOREGULATION AND INFECTION LABORATORY
|
| Street address |
1 Midland Road
|
| City |
London |
| ZIP/Postal code |
NW1 1AT |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (760)
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| Relations |
| BioProject |
PRJNA662344 |
| SRA |
SRP281425 |
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