|
| Status |
Public on Mar 15, 2021 |
| Title |
Transcriptional profiles of kidney upon HNF4A loss in mice by RNA-seq |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Adult-onset knockout of HNF4A resulted in decreased expression levels of brush border genes. We find a robust shift in the transcriptome away from proximal tubule transcripts and towards distal tubule transcripts in the kidney upon HNF4A loss.
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| |
|
| Overall design |
Transcriptional profiling was employed to identify HNF4A-dependent gene expression in the mouse kidney
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| |
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| Contributor(s) |
Chen L, Aita R, Verzi MP |
| Citation(s) |
34001900 |
| Submission date |
Sep 14, 2020 |
| Last update date |
Jun 14, 2021 |
| Contact name |
Michael P Verzi |
| Organization name |
Rutgers, the State University of New Jersey
|
| Department |
Genetics
|
| Lab |
Verzi
|
| Street address |
145 Bevier Road
|
| City |
Piscataway |
| State/province |
NJ |
| ZIP/Postal code |
08854 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA663326 |
| SRA |
SRP282343 |
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