|
| Status |
Public on Dec 15, 2020 |
| Title |
TgIF2K-B is an eIF2α kinase in Toxoplasma gondii that responds to oxidative stress and optimizes pathogenicity |
| Organism |
Toxoplasma gondii |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Here we report on gene expression changes in T. gondii in response to oxidative stress induced by sodium arsonite in wild-type and TgIF2K-B knockout intracellular parasites.
|
| |
|
| Overall design |
total RNA seq conducted on purified wild-type and TgIF2K-B KO parasites following sodium arsonite or no treatment
|
| Web link |
https://www.biorxiv.org/content/10.1101/2020.09.24.312744v1
|
| |
|
| Contributor(s) |
Augusto L, Martynowicz J, Amin PH, Carlson KR, Wek RC, Sullivan WJ Jr |
| Citation(s) |
33500345 |
| |
| Submission date |
Sep 18, 2020 |
| Last update date |
Feb 08, 2021 |
| Contact name |
Ronald C Wek |
| E-mail(s) |
rwek@iu.edu
|
| Organization name |
Indiana University School of Medicine
|
| Department |
Biochemistry and Molecular Biology
|
| Street address |
635 N. Barnhill Dr. MS4067
|
| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46202 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL23466 |
Illumina HiSeq 4000 (Toxoplasma gondii) |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA664394 |
| SRA |
SRP283886 |
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