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Status |
Public on Nov 14, 2020 |
Title |
DUSP11-mediated Control of 5’-Triphosphate RNA Regulates RIG-I Sensitivity |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Mice lacking DUSP11 display enhanced interferon signaling signature
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Overall design |
RNA extracted from liver (n=24) or spleen (n=6) of wild-type (n=15) and DUSP11-deficient (n=15) mice subjected to immune-stimulatory 5'-ppp RNA treatment (n=12 liver, 8 male/4 female), mock treatment (n=6 liver, 2 male/4 female; n=6 spleen, 2 male/4 female), or untreated (n=6 liver, 4 male/2 female). Mice were age/sex pair-matched within each treatment.
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Contributor(s) |
Choi JH, Burke JM, Szymanik KH, Nepal U, Battenhouse A, Lau JT, Stark A, Lam V, Sullivan CS |
Citation(s) |
33184222 |
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Submission date |
Sep 30, 2020 |
Last update date |
Feb 13, 2021 |
Contact name |
Anna Battenhouse |
Organization name |
The University of Texas at Austin
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Department |
Center for Biomedical Research Support
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Lab |
Bioinformatics Consulting Group
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Street address |
100 East 24th St., Stop A5000
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City |
Austin |
State/province |
TX |
ZIP/Postal code |
78712 |
Country |
USA |
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Platforms (1) |
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Samples (30)
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Relations |
BioProject |
PRJNA666674 |
SRA |
SRP285938 |