|
| Status |
Public on Nov 05, 2004 |
| Title |
INS-1 cell lines (FLP-In T-REx) |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
Four rat insulinoma cell lines (INS-1) were generated that contain a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the cell lines contain the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors or other signal tranduction molecules can be identified. The expression profiles of the parental INS-1 cell line and the four derivatives were determined on a RAE230A array, showing that the highly differentiated phenotype of the parental cell line was maintained in the clones.
Keywords: ordered
|
| |
|
| |
|
| Contributor(s) |
Thomas H, Senkel S, Erdmann S, Arndt T, Turan G, Klein-Hitpass L, Ryffel GU |
| Citation(s) |
15520459 |
| Submission date |
Jul 23, 2004 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Ludger Klein-Hitpass |
| E-mail(s) |
ludger.klein-hitpass@uni-essen.de
|
| Phone |
+49 201 723 85552
|
| Organization name |
Institut fuer Zellbiologie
|
| Department |
Universitaetsklinikum
|
| Lab |
BioChip Lab
|
| Street address |
Virchowstr. 173
|
| City |
Essen |
| ZIP/Postal code |
D-45122 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
|
| Samples (5)
|
| GSM27203 |
INS-1 |
| GSM27204 |
INS-1 cell line (FLP-In T-REx clone #1-1.2) |
| GSM27205 |
INS-1 cell line (FLP-In T-REx clone #1-1.16) |
| GSM27206 |
INS-1 cell line (FLP-In T-REx clone #5-3.14) |
| GSM27207 |
INS-1 cell line (FLP-In T-REx clone #5-3.19) |
|
| This SubSeries is part of SuperSeries: |
| GSE6428 |
HNF1b, HNF4a2 and HNF6 targets |
|
| Relations |
| BioProject |
PRJNA104745 |
Less...
More...