GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE1591 Query DataSets for GSE1591
Status Public on Nov 05, 2004
Title INS-1 cell lines (FLP-In T-REx)
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary Four rat insulinoma cell lines (INS-1) were generated that contain a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the cell lines contain the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors or other signal tranduction molecules can be identified. The expression profiles of the parental INS-1 cell line and the four derivatives were determined on a RAE230A array, showing that the highly differentiated phenotype of the parental cell line was maintained in the clones.
Keywords: ordered
Contributor(s) Thomas H, Senkel S, Erdmann S, Arndt T, Turan G, Klein-Hitpass L, Ryffel GU
Citation(s) 15520459
Submission date Jul 23, 2004
Last update date Mar 03, 2017
Contact name Ludger Klein-Hitpass
Phone +49 201 723 85552
Organization name Institut fuer Zellbiologie
Department Universitaetsklinikum
Lab BioChip Lab
Street address Virchowstr. 173
City Essen
ZIP/Postal code D-45122
Country Germany
Platforms (1)
GPL341 [RAE230A] Affymetrix Rat Expression 230A Array
Samples (5)
GSM27203 INS-1
GSM27204 INS-1 cell line (FLP-In T-REx clone #1-1.2)
GSM27205 INS-1 cell line (FLP-In T-REx clone #1-1.16)
This SubSeries is part of SuperSeries:
GSE6428 HNF1b, HNF4a2 and HNF6 targets
BioProject PRJNA104745

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary data files not provided

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap