|
| Status |
Public on Jun 07, 2021 |
| Title |
The human β-globin enhancer LCR HS2 plays a role in forming a TAD by activating chromatin structure at neighboring CTCF sites |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We propose that the HS2 has a role in forming a β-globin TAD by activating neighboring CTCF sites and the role is beyond typical enhancer activity.
|
| |
|
| Overall design |
H3K27ac, H3K27me3 ChIP-seq was performed in control and LCR HS2 deletion cells.
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| |
|
| Contributor(s) |
Kim A |
| Citation(s) |
34033138 |
| |
| Submission date |
Oct 06, 2020 |
| Last update date |
Jun 13, 2021 |
| Contact name |
AeRi Kim |
| E-mail(s) |
kang3000j@pusan.ac.kr
|
| Organization name |
Pusan national university
|
| Street address |
2, Busandaehak-ro 63beon-gil, Geumjeong-gu
|
| City |
Busan |
| ZIP/Postal code |
46241 |
| Country |
South Korea |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA667735 |
| SRA |
SRP286563 |
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