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Series GSE159557 Query DataSets for GSE159557
Status Public on Oct 16, 2023
Title Integrative analysis of transcriptomic and epigenomic dynamics of liver organoids using single cell RNA-seq and ATAC-seq.
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary In this study, to identify the heterogeneity and dynamics of transcriptome and epigenome of liver organoid in single cell level, we applied single cell RNA-seq (scRNA-seq) and single cell ATAC-seq (scATAC-seq) using Chromium’s 10x platform. We analyzed liver organoids treated with two medium conditions (hepatic medium - HM and differentiation medium - DM).
 
Overall design For DM and HM liver organoids, single cell RNA-seq and single cell ATAC-seq was performed with repliacte using 10X Genomics Single Cell Solution.
Web link https://www.sciencedirect.com/science/article/pii/S2589004223017522?via%3Dihub
 
Contributor(s) Mun SJ, Son MJ, Kim J, Kim S
Citation(s) 37680467
Submission date Oct 19, 2020
Last update date Jan 15, 2024
Contact name Jong Hwan Kim
E-mail(s) kkjjhhk@kribb.re.kr
Phone 0821093299557
Organization name Korea Research Institute of Bioscience and Biotechnology
Department Genome structure research center
Street address 125 Gwahak-ro, Yuseong-gu
City Daejeon
ZIP/Postal code ASI|KR|KS015|DAEJEON
Country South Korea
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (8)
GSM4832481 DM_1_scRNAseq
GSM4832482 DM_2_scRNAseq
GSM4832483 HM_1_scRNAseq
Relations
BioProject PRJNA669699
SRA SRP287503

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE159557_RAW.tar 1.3 Gb (http)(custom) TAR (of BED, MTX, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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