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| Status |
Public on Jan 11, 2022 |
| Title |
Expression profiles of tRNA-derived small RNAs and their potential roles in primary nasopharyngeal carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Transfer-RNA-Derived Small RNA (tsRNA) is a novel class of short non-coding RNA including stress-induced tRNA fragments (tiRNA) and tRNA-derived fragments (tRF). Using RNA sequencing, we evaluated the tsRNA expression profiles in the fresh nasopharyngeal carcinoma tissue specimens (n = 4) and mucosal tissue specimens (n = 4) in patients’ primary nasopharyngeal carcinoma (P-NPC) and nasopharyngitis. Bioinformatics analyses indicated that tsRNAs were the important regulators and potential new biomarkers of P-NPC.
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| |
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| Overall design |
tiRNA and tRF profiles in the tissue specimens of primary nasopharyngeal carcinoma (P-NPC) and nasopharyngitis patients, in triplicate, using Illumina NextSeq 500 system.
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| |
|
| Contributor(s) |
Lu Z, Ma S, Li H |
| Citation(s) |
34988117 |
| |
| Submission date |
Oct 21, 2020 |
| Last update date |
Jan 12, 2022 |
| Contact name |
Zhaoyi Lu |
| E-mail(s) |
lzy.fai@live.cn
|
| Organization name |
The First Affiliated Hospital of Bengbu Medical College
|
| Department |
Department of Otolaryngology
|
| Street address |
287 Changhuai Road
|
| City |
Bengbu |
| State/province |
Anhui |
| ZIP/Postal code |
233004 |
| Country |
China |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA670406 |
| SRA |
SRP287971 |
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