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Status |
Public on Jan 11, 2022 |
Title |
Expression profiles of tRNA-derived small RNAs and their potential roles in primary nasopharyngeal carcinoma |
Organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by high throughput sequencing
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Summary |
Transfer-RNA-Derived Small RNA (tsRNA) is a novel class of short non-coding RNA including stress-induced tRNA fragments (tiRNA) and tRNA-derived fragments (tRF). Using RNA sequencing, we evaluated the tsRNA expression profiles in the fresh nasopharyngeal carcinoma tissue specimens (n = 4) and mucosal tissue specimens (n = 4) in patients’ primary nasopharyngeal carcinoma (P-NPC) and nasopharyngitis. Bioinformatics analyses indicated that tsRNAs were the important regulators and potential new biomarkers of P-NPC.
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Overall design |
tiRNA and tRF profiles in the tissue specimens of primary nasopharyngeal carcinoma (P-NPC) and nasopharyngitis patients, in triplicate, using Illumina NextSeq 500 system.
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Contributor(s) |
Lu Z, Ma S, Li H |
Citation(s) |
34988117 |
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Submission date |
Oct 21, 2020 |
Last update date |
Jan 12, 2022 |
Contact name |
Zhaoyi Lu |
E-mail(s) |
lzy.fai@live.cn
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Organization name |
The First Affiliated Hospital of Bengbu Medical College
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Department |
Department of Otolaryngology
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Street address |
287 Changhuai Road
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City |
Bengbu |
State/province |
Anhui |
ZIP/Postal code |
233004 |
Country |
China |
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Platforms (1) |
GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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Samples (8)
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Relations |
BioProject |
PRJNA670406 |
SRA |
SRP287971 |