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| Status |
Public on Nov 30, 2020 |
| Title |
Expression data from Plasmodium falciparum |
| Platform organisms |
Plasmodium falciparum; Anopheles gambiae |
| Sample organism |
Plasmodium falciparum |
| Experiment type |
Expression profiling by array
|
| Summary |
Artemisinin and its derivatives exert the potent, antimalarial action, although the mechanisms by which these drugs inhibit the growth of mararia parasites is not fully understood.
We used microarrays to detail the global gene expression change in early erythrocytic P. falciparum, and identified molecules that may contribute to the activity of dihydroartemisinin.
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| |
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| Overall design |
To identify genes differentially expressed in P. falciparum exposed to dihydroartemisinin other drugs 7-benzylidenealtrexone and rimonaband were also analyzed.
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| Contributor(s) |
Asahi H, Wada A |
| Citation(s) |
37321567 |
| |
| Submission date |
Nov 02, 2020 |
| Last update date |
Jul 18, 2023 |
| Contact name |
Hiroko Asahi |
| E-mail(s) |
hiroko.asahi@riken.jp
|
| Phone |
+81-45-503-9205
|
| Organization name |
RIKEN Center for Biosystems Dynamics Research
|
| Lab |
Laboratory for Nonnatural Amino Acid Technology
|
| Street address |
1-7-22, Suehiro-cho, Tsurumi-ku
|
| City |
Yokohama |
| State/province |
Kanagawa |
| ZIP/Postal code |
230 0045 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL1321 |
[Plasmodium_Anopheles] Affymetrix Plasmodium/Anopheles Genome Array |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA673891 |
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