|
Status |
Public on May 11, 2021 |
Title |
MicroRNAs involved in regeneration of adult zebrafish brain. |
Organism |
Danio rerio |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
For its remarkable ability to heal injuries of the adult central nervous system, the zebrafish has become an important model to investigate neural regeneration. Despite big progresses in our understanding of some of the underlying key processes, a comprehensive analysis of the changes of the transcriptome has not been reported yet. We analysed here the transcriptome of the regenerating telencephalon for changes in the expression of microRNAs and their putative targets.
|
|
|
Overall design |
small RNA sequencing of injured and control adult zebrafish telencephalic hemisphere
|
|
|
Contributor(s) |
Gourain V, Armant O, Straehle U |
Citation(s) |
- Gourain V, Armant O, Lübke L, Diotel N et al. Multi-Dimensional Transcriptome Analysis Reveals Modulation of Cholesterol Metabolism as Highly Integrated Response to Brain Injury. Front Neurosci 2021;15:671249. PMID: 34054419
- Lübke L, Zhang G, Strähle U, Rastegar S. mdka Expression Is Associated with Quiescent Neural Stem Cells during Constitutive and Reactive Neurogenesis in the Adult Zebrafish Telencephalon. Brain Sci 2022 Feb 18;12(2). PMID: 35204047
|
|
Submission date |
Nov 06, 2020 |
Last update date |
Mar 04, 2022 |
Contact name |
Victor GOURAIN |
Organization name |
Centre de recherche en transplantation et immunologie
|
Department |
UMR1064
|
Street address |
30 Bd Jean Monnet
|
City |
Nantes |
ZIP/Postal code |
44093 |
Country |
France |
|
|
Platforms (1) |
GPL18171 |
Illumina HiSeq 1500 (Danio rerio) |
|
Samples (6)
|
|
Relations |
BioProject |
PRJNA675087 |
SRA |
SRP291443 |