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| Status |
Public on Dec 08, 2020 |
| Title |
A longitudinal and transancestral analysis of DNA methylation patterns and disease activity in lupus patients |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
Epigenetic dysregulation is implicated in the pathogenesis of lupus. We performed a longitudinal analysis to assess changes in DNA methylation in neutrophils collected from 54 lupus patients over 4 years of follow up and across disease activity levels using 229 patient samples.
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| |
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| Overall design |
Illumina Infinium MethylationEPIC array of genomic DNA from neutrophils extracted from whole blood from 54 systemic lupus erythematosus (SLE) patients over time for a total of 229 timepoints.
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| Contributor(s) |
Sawalha AH, Coit P |
| Citation(s) |
33108347 |
| |
| Submission date |
Nov 13, 2020 |
| Last update date |
Dec 08, 2020 |
| Contact name |
Amr Sawalha |
| E-mail(s) |
asawalha@pitt.edu
|
| Organization name |
University of Pittsburgh
|
| Street address |
4401 Penn Avenue
|
| City |
Pittsburgh |
| State/province |
PA |
| ZIP/Postal code |
15224 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (229)
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| Relations |
| BioProject |
PRJNA678368 |
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