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| Status |
Public on Nov 23, 2023 |
| Title |
Next generation sequencing of circular RNAs in diabetes mellitus rats after sleeve gastrectomy |
| Organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Sleeve gastrectomy (SG) can improve diabetes mellitus dramatically. However, the mechanisms remain largely undetermined. With the advancement of in-depth bioinformatic analysis, non-coding RNAs especially circular RNAs(circRNAs), have been implicated in many biological processes. To explore whether circRNAs mediate the amelioration of diabetes mellitus after SG, we subjected liver samples of diabetic rats after SG and shame operations for RNA sequencing. Through RNA sequencing, we identified a dramatically differentially expressed profile of 107 circRNAs. Some of these specific circRNAs were only expressed in diabetic rats after SG, which may be promising biological markers of SG prognosis.
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| Overall design |
Expression profile of circular RNAs in diabetes mellitus rats after sleeve gastrectomy
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| Contributor(s) |
Li L, Hu S |
| Citation missing |
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| |
| Submission date |
Nov 23, 2020 |
| Last update date |
Nov 23, 2023 |
| Contact name |
Linchuan Li |
| E-mail(s) |
linchuanlee@hotmail.com
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| Organization name |
Shandong University
|
| Street address |
16766# Jingshi Road
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| City |
Jinan |
| State/province |
Shandong |
| ZIP/Postal code |
250000 |
| Country |
China |
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| Platforms (1) |
| GPL22396 |
Illumina HiSeq 4000 (Rattus norvegicus) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE162022 |
Next generation sequencing of circular and lnc RNAs in diabetes mellitus rats after sleeve gastrectomy |
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| Relations |
| BioProject |
PRJNA680322 |
| SRA |
SRP293936 |
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