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Series GSE162013 Query DataSets for GSE162013
Status Public on Nov 23, 2023
Title Next generation sequencing of circular RNAs in diabetes mellitus rats after sleeve gastrectomy
Organism Rattus norvegicus
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Sleeve gastrectomy (SG) can improve diabetes mellitus dramatically. However, the mechanisms remain largely undetermined. With the advancement of in-depth bioinformatic analysis, non-coding RNAs especially circular RNAs(circRNAs), have been implicated in many biological processes. To explore whether circRNAs mediate the amelioration of diabetes mellitus after SG, we subjected liver samples of diabetic rats after SG and shame operations for RNA sequencing. Through RNA sequencing, we identified a dramatically differentially expressed profile of 107 circRNAs. Some of these specific circRNAs were only expressed in diabetic rats after SG, which may be promising biological markers of SG prognosis.
Overall design Expression profile of circular RNAs in diabetes mellitus rats after sleeve gastrectomy
Contributor(s) Li L, Hu S
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Submission date Nov 23, 2020
Last update date Nov 23, 2023
Contact name Linchuan Li
Organization name Shandong University
Street address 16766# Jingshi Road
City Jinan
State/province Shandong
ZIP/Postal code 250000
Country China
Platforms (1)
GPL22396 Illumina HiSeq 4000 (Rattus norvegicus)
Samples (12)
GSM4929725 re_DM1
GSM4929726 re_DM2
GSM4929727 SG1
This SubSeries is part of SuperSeries:
GSE162022 Next generation sequencing of circular and lnc RNAs in diabetes mellitus rats after sleeve gastrectomy
BioProject PRJNA680322
SRA SRP293936

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Supplementary file Size Download File type/resource
GSE162013_1_circRNA_expression.txt.gz 4.2 Mb (ftp)(http) TXT
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