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Series GSE162767 Query DataSets for GSE162767
Status Public on Dec 06, 2023
Title Single cell-seq identify discoid lateral meniscus
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Discoid lateral meniscus (DLM) is more prone to injury than a normally shaped meniscus. Our previous study successfully identified the different cell types and their corresponding marker genes in meniscus tissues, but there was no study comparing the gene expression and cell heterogenicity of discoid meniscus with normal meniscus.
 
Overall design scRNA-seq was used to identify cell subsets and their gene signatures in DLM and osteoarthritis lateral meniscus (OAM) cells to determine their differentiation relationships and identify specific cell types. Pseudotime analysis and immunohistochemical staining were used to investigate temporal and spatial distribution of DLM specific clusters
 
Contributor(s) Sun H, Ma R
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Dec 07, 2020
Last update date Dec 06, 2023
Contact name Hao Sun
E-mail(s) sunhaojnsysu@foxmail.com
Phone 15017541945
Organization name First Affiliated Hospital of Sun Yat-sen University,
Department Joint surgery
Street address Zhongshan 2nd Road
City Guangzhou
State/province Guangdong
ZIP/Postal code 510220
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (2)
GSM4959543 OA-CON
GSM4959544 OA-DLM
Relations
BioProject PRJNA682995
SRA SRP296773

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE162767_AllSample.counts.tsv.gz 17.9 Mb (ftp)(http) TSV
GSE162767_OA-con.cellname.list.txt.gz 36.3 Kb (ftp)(http) TXT
GSE162767_OA-pan.cellname.list.txt.gz 35.4 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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