GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE16352 Query DataSets for GSE16352
Status Public on Jan 01, 2010
Title Transcriptional analysis of the Neisseria gonorrhoeae Fur regulon
Platform organisms Neisseria gonorrhoeae; Neisseria meningitidis
Sample organism Neisseria gonorrhoeae FA 1090
Experiment type Expression profiling by array
Summary In Neisseria gonorrhoeae, Fur (ferric uptake regulator) protein regulates iron homeostasis gene expression through binding to conserved sequences in promoters of iron-responsive genes. We have expanded the gonococcal Fur regulon using a custom microarray to monitor iron-responsive gene expression throughout the growth curve combined with a genome-wide in silico analysis to predict Fur boxes (FB), and in vivo FuRTA assays to detect genes able to bind Fur.

Keywords: time course: (1hr ,2hr, 3hr, 4hr)
Overall design The effect of iron on global gene expression was determined over a 4-h time period by comparing the RNA profile of the organism grown in iron-deplete conditions to growth in iron-replete conditions.
Contributor(s) Jackson L, Ducey T, Zaitshik J, Orvis J, Dyer D
Citation(s) 19854902
Submission date May 31, 2009
Last update date Mar 21, 2012
Contact name Lydgia Jackson
Phone 405 271-1201
Fax 405 271-1204
Organization name University of Oklahoma Health Sciences Center
Department Microbiology and Immunology
Lab Dyer
Street address 975 NE 10th Street
City Oklahoma City
State/province OK
ZIP/Postal code 73104
Country USA
Platforms (1)
GPL7320 OUHSC Dyer Neisseria gonorrhoeae 2K MPAUT1a520274F
Samples (24)
GSM410631 Fe- 1hr replicate 1
GSM410632 Fe- 1hr replicate 2
GSM410633 Fe- 1hr replicate 3
BioProject PRJNA115309

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE16352_RAW.tar 52.3 Mb (http)(custom) TAR (of CEL)
GSE16352_README.txt 907 b (ftp)(http) TXT
GSE16352_chip_protocol.txt.gz 1.0 Kb (ftp)(http) TXT
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap