|
| Status |
Public on Jan 21, 2021 |
| Title |
RNA seq of sorted T cell subsets from PBMCs and rectal biopsies from humans and rhesus macaques |
| Organisms |
Macaca mulatta; Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Memory CD4 T cells facilitate HIV establishment following transmission and contribute to HIV persistence during suppressive antiretroviral therapy (ART). Numerous studies have highlighted the importance of memory CD4 T cells expressing the surface integrin heterodimer, α4β7 in HIV infection. Here, we focused on delineating the molecular characteristics of α4β7+ CD4 T cells and determining how transcriptional profiles of circulating α4β7hi CD4 T cells corresponded to that within the lower GI tract.
|
| |
|
| Overall design |
Comparision of transciptome profiles across blood and gut compartment
|
| |
|
| Contributor(s) |
Iyer SS |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 20, 2021 |
| Last update date |
Jan 24, 2021 |
| Contact name |
Smita Iyer |
| E-mail(s) |
smiyer@ucdavis.edu
|
| Organization name |
University of California-Davis
|
| Department |
Center for Immunology and Infectious Disease
|
| Street address |
county rd 98 & hutchison, ccm room 2075
|
| City |
Davis |
| State/province |
CA |
| ZIP/Postal code |
95616 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL23949 |
Illumina HiSeq 4000 (Macaca mulatta) |
|
| Samples (70)
|
|
| Relations |
| BioProject |
PRJNA693560 |
| SRA |
SRP302591 |
Less...
More...