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| Status |
Public on Apr 13, 2022 |
| Title |
Dynamic circRNAs expression profiles and circRNA-associated-ceRNA networks during B-cell development and differentiation in mouse bone marrow |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Our findings further expand the current knowledge regarding the biology of ceRNAs and their regulatory roles in B-cell development and differentiation process. These newly discovered networks provide more ideas for further research about B-cell development in the future.
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| Overall design |
we used miRNA sequencing and LncRNA sequencing to detect several develoment stages of B-cell sorted from mouse bone marrow by using FACS (Pro-B cells, Pre-B cells, Immature B cells and mature Bcells) to study the underlying biological mechanisms in the rapid development of B-cell.
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| |
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| Contributor(s) |
Zhang W, Hu S, Pan J |
| Citation(s) |
35386709 |
| |
| Submission date |
Feb 03, 2021 |
| Last update date |
Apr 13, 2022 |
| Contact name |
Saineng Hu |
| E-mail(s) |
saineng_hu@pku.edu.cn
|
| Phone |
+86-181-7315-6861
|
| Organization name |
Shenzhen Peking University - The Hong Kong University of Science and Technology Medical Center
|
| Department |
Biomedical Research Institute
|
| Street address |
Lianhua Road Futian District
|
| City |
Shenzhen |
| ZIP/Postal code |
518000 |
| Country |
China |
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| Platforms (2) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA699300 |
| SRA |
SRP304593 |
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