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| Status |
Public on May 18, 2021 |
| Title |
Segmental chromatin states |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
We profiled the chromatin accessibility, transcription factor binding, and gene expression in the homologous wing and haltere imaginal disc of Drosophila melanogaster, which are distinguished by the expression of the Hox protein Ultrabithorax (Ubx). Through the analysis of chromatin changes, we show Ubx has widespread effects on the chromatin landscape to specify cell identity.
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| Overall design |
Using ATAC-seq to profile chromatin accessibility and ChIP-seq to assess genome-wide TF binding patterns
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| Contributor(s) |
Loker R, Mann RS |
| Citation(s) |
34358443, 35475221 |
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| Submission date |
Feb 12, 2021 |
| Last update date |
May 05, 2022 |
| Contact name |
Ryan Loker |
| E-mail(s) |
rel2150@columbia.edu
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| Phone |
(212) 305-2111
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| Organization name |
Columbia University
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| Street address |
3227 Broadway
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10032 |
| Country |
USA |
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| Platforms (1) |
| GPL19132 |
Illumina NextSeq 500 (Drosophila melanogaster) |
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| Samples (36)
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| Relations |
| BioProject |
PRJNA701668 |
| SRA |
SRP306242 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE166714_RAW.tar |
3.3 Gb |
(http)(custom) |
TAR (of BIGWIG, CSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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