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Series GSE167345 Query DataSets for GSE167345
Status Public on Feb 24, 2021
Title lncRNA profiles enable prognosis prediction and subtyping for esophageal squamous cell carcinoma
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary AC007128.1, a long non-coding RNA, was upregulated in both ESCC tissues and cells, and associated with poor prognosis in ESCC. AC007128.1 can promote migration and invasion in ESCC cell lines. By RNA-sequencing analysis, we observed the significant changes of genes important in AC007128.1-depleted cells. We generated two KYSE150 cell lines stably transduced with either a sh-NC lentiviral construct or a shRNA lentiviral construct designed to target AC007128.1 RNA to investigate the consequences on the gene expression profile of AC007128.1 knockdown in KYSE150 cells.
 
Overall design The gene expression of 3 samples from shAC007128.1 KYSE150 cell line was compared to 3 samples from shCtrl by RNA sequencing.
 
Contributor(s) Zhang S
Citation(s) 34127945
Submission date Feb 23, 2021
Last update date Jun 30, 2021
Contact name chuanxin wang
E-mail(s) cxwang@sdu.edu.cn
Organization name The Second Hospital of Shandong University
Street address 247 Beiyuan Street, Jinan 250033, Shandong, China,
City Jinan
ZIP/Postal code 250033
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM5102582 KYSE150_shNC_1 RNA-seq
GSM5102583 KYSE150_shNC_2 RNA-seq
GSM5102584 KYSE150_shNC_3 RNA-seq
Relations
BioProject PRJNA704364
SRA SRP307746

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE167345_gene_count_matrix.txt.gz 540.4 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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