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Series GSE167362 Query DataSets for GSE167362
Status Public on Feb 24, 2021
Title Using lncRNA sequencing to reveal a putative lncRNA-mRNA correlation network and potential role of PCBP1-AS1 in pathogenesis of cervical cancer
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary The aim of this study was to construct a lncRNA-mRNA co-expression function network and analyze lncRNAs that might contribute to the pathogenesis of cervical cancer. Transcriptome analysis of 3 cervical cancer samples and 3 adjacent tissue samples was completed in this project.LncRNA-mRNA correlation analysis, enrichment of functions, qPCR, K-M survival, clinicopathology analysis, GSEA and immune infiltration analysis were implemented. Total of 67.600 GB of Clean Data (sequencing Data after quality control) was obtained. The average amount of Clean Data of each sample was 11.267 GB, the percentage of Q30 base was above 91.18%, and the GC content was between 45.46% and 47.18%.Reference species: human;Reference genomic version: GRCH38;Reference genome source: http://asia.ensembl.org/Homo_sapiens/Info/Index;The sequencing data of each sample after quality control was compared with the specified reference genome, and the matching rates ranged from 95.957% to 97.270%, and the unique matching rates ranged from 91.363% to 94.258%. Transcriptomic and lncRNA-mRNA correlation analysis revealed PCBP1-AS1 plays a key role as an independent prognostic factor in patients with cervical cancer.
 
Overall design LncRNA profiles of 3 cervical cancer samples and 3 adjacent tissue samples
 
Contributor(s) Li L, Peng Q, Gong M, Ling L, Xu Y, Liu Q
Citation(s) 33833992
Submission date Feb 23, 2021
Last update date Jun 01, 2021
Contact name linhan li
E-mail(s) peiyongyan@gdpu.edu.cn
Organization name Affiliated Jiangning Hospital of Nanjing Medical University
Street address 168 Gushan Road, Dongshan Street, Jiangning District
City Nanjing
ZIP/Postal code 211100
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM5102894 DAQCA
GSM5102895 DAQZC
GSM5102896 XHXCA
Relations
BioProject PRJNA704389
SRA SRP307765

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE167362_matrix_gene.count.txt.gz 139.8 Kb (ftp)(http) TXT
GSE167362_matrix_gene.fpkm.txt.gz 407.6 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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