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| Status |
Public on Jan 01, 2022 |
| Title |
Histone H3K4me3 signal breadth reveals constitutive and hypoxia stress responsive endometrial functions linked to endometriosis |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
We report sequening of chromatin immunoprecipitated DNA (ChIP-Seq) of histone H3 at lysine 4 (H3K4me3) normoxic and hypoxia treated endometrial stromal fibroblasts (ESF) and hypoxia treated differentiated decidual stromal cells (DSC),
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| Overall design |
We conducted H3K4me3 ChIP-seq in hypoxia treated (16 h, 1% O2) undifferentiated endometrial stromal fibroblasts (ESF) and differentiated decidual stromal cells (DSC) and compared the H3K4me3 marks to those in normoxia. For DSC, before hypoxia treatment ESF were in vitro decidulized with cAMP and progesterone (MPA) for 2 days.
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| Contributor(s) |
Rytkönen KT, Nnamani MC |
| Citation(s) |
35494227 |
| |
| Submission date |
Mar 01, 2021 |
| Last update date |
May 05, 2022 |
| Contact name |
Kalle T Rytkönen |
| E-mail(s) |
katury@utu.fi
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| Organization name |
Yale University
|
| Department |
EEB, Systems Biology institute
|
| Lab |
Gunter Wagner Lab
|
| Street address |
840 West Campus Drive
|
| City |
West Haven |
| State/province |
CT |
| ZIP/Postal code |
06516 |
| Country |
USA |
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| Platforms (1) |
| GPL9115 |
Illumina Genome Analyzer II (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA705652 |
| SRA |
SRP308683 |
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