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Status |
Public on Mar 01, 2024 |
Title |
(Pro)renin receptor inhibition reduces plasma cholesterol and triglycerides but does not attenuate atherosclerosis in atherosclerotic mice |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Purpose: to clarify the transcriptomic changes in aortic arch of inhibiting the (pro)renin receptor using (P)RR G-ASOs
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Overall design |
Aortic arch isolated from non treated 8 week-old LDLR-/- mice (0 week control), 8-week-old LDLR-/- mice that received saline treatment and fed with WTD for 4 weeks, and 8-week-old LDLR-/- mice that received (P)RR G-ASOs treatment and fed with WTD for 4 weeks
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Contributor(s) |
Lu X, Ye D |
Citation missing |
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Submission date |
Mar 01, 2021 |
Last update date |
Mar 01, 2024 |
Contact name |
lu xi feng |
E-mail(s) |
xifeng.lu@outlook.com
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Phone |
+8613168778436
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Organization name |
Shenzhen University
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Street address |
Taoyuan
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City |
Shenzhen |
State/province |
Guangdong |
ZIP/Postal code |
518000 |
Country |
China |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (3) |
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Relations |
BioProject |
PRJNA705690 |
SRA |
SRP308714 |