|
| Status |
Public on Jan 21, 2022 |
| Title |
Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology. |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Other
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Citation(s) |
35020836 |
| |
| Submission date |
Mar 17, 2021 |
| Last update date |
Jan 23, 2022 |
| Contact name |
Nadine Fournier |
| E-mail(s) |
nadine.fournier@sib.swiss
|
| Organization name |
Agora Cancer Research Center & Swiss Institute of Bioinformatics
|
| Lab |
Translational Data Science Facility
|
| Street address |
Agora Cancer Research Center, Bugon 25A
|
| City |
Lausanne |
| State/province |
Vaud |
| ZIP/Postal code |
1000 |
| Country |
Switzerland |
| |
|
| Platforms (3) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (61)
|
|
| This SuperSeries is composed of the following SubSeries:
|
| GSE169116 |
Gene expression profiling of LSK cells with hyperactivated Notch1 and/or Tcf7 knock-out [RNA-seq] |
| GSE169117 |
Genome-wide histone mark and CTCF profiling of LSK cells with hyperactivated Notch1 and/or Tcf7 knock-out [ChIP-seq] |
| GSE169118 |
Chromatin accessibility profiling of LSK cells with hyperactivated Notch1 and/or Tcf7 knock-out [ATAC-seq_mouse] |
| GSE169119 |
Chromatin accessibility analysis of human cord blood cells with hyperactivated Notch1 [ATAC-seq_human] |
| GSE169120 |
3D chromatin topography of LSK cells with hyperactivated Notch1 and/or Tcf7 knock-out [HiC-seq] |
|
| Relations |
| BioProject |
PRJNA715475 |
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