|
| Status |
Public on Jul 08, 2010 |
| Title |
Gene expression of Kit225 cells upon NC1153 treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
NC1153 was shown to inhibit JAK3 tyrosine kinase. Lymphocytes survival depends on the integrity of STAT5, the primary downstream target of JAK3.
In this study microarrays were used to test the effect of a JAK3 inhibitor, NC1153, on the gene expression profile of a human leukemia cell line.
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| |
|
| Overall design |
Kit225 human leukemia cells were treated with NC1153 or DMSO (vehicle) for 12 h then harvested for RNA isolation.
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| |
|
| Contributor(s) |
Nagy ZS |
| Citation(s) |
20211620 |
| |
| Submission date |
Jul 08, 2009 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Zsuzsanna S. Nagy |
| Organization name |
University of Debrecen
|
| Department |
Biochemistry and Molecular Biology
|
| Street address |
Nagyerdei krt. 98
|
| City |
Debrecen |
| ZIP/Postal code |
H-4032 |
| Country |
Hungary |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (4)
|
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| Relations |
| BioProject |
PRJNA117747 |
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