|
| Status |
Public on Dec 21, 2022 |
| Title |
Role of the HCMV immediate early proteins in controlling the HCMV and cellular epigenomes |
| Organisms |
Homo sapiens; Human betaherpesvirus 5 |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Purpose: to investigate the role of the HCMV immediate early proteins in controlling the HCMV and cellular epigneomes during lytic infectioin
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| |
|
| Overall design |
MRC5 cells were infected with TB40r mGFP-IE-FKBP strain of HCMV. Infected cells were cultured for 5 days in the presence or absence of shield-1. Infected cells were harvested and processed for Pol 2 and H3K27Ac ChIP-seq analysis.
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| |
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| Contributor(s) |
Hummel M, Forte E, Schipma M |
| Citation(s) |
36645269 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P01 AI112522 |
Integrating Mechanistic Insights from Diverse Models to Prevent CMV Reactivation following Transplantation |
NORTHWESTERN UNIVERSITY AT CHICAGO |
MARY A HUMMEL |
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| |
| Submission date |
Apr 05, 2021 |
| Last update date |
Mar 22, 2023 |
| Contact name |
Mary Hummel |
| E-mail(s) |
m-hummel@northwestern.edu
|
| Phone |
847-322-6438
|
| Organization name |
Northwestern University
|
| Street address |
303 E. Chicago Ave
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60611 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL29977 |
Illumina NovaSeq 6000 (Homo sapiens; Human betaherpesvirus 5) |
|
| Samples (16)
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| Relations |
| BioProject |
PRJNA719829 |
| SRA |
SRP313553 |
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