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| Status |
Public on Apr 20, 2021 |
| Title |
Effects of a single dose of psilocybin on behaviour, brain 5-HT2A receptor occupancy and gene expression in the pig |
| Organism |
Sus scrofa |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
mRNA sequencing of pig prefrontal cortex after treatment with one dose of psilocybin or placebo (saline).
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| Overall design |
Adolescent female Danish slaughter pigs of 20kg were used. A single dose of 0.08mg/kg psilocybin or saline was administered iv while the pig was awake and freely roaming around. Either 1day or 1 week later the pigs were euthanized by iv pentobarbital overdose. N=6/group: Saline 1day; Psilocybin 1day, Saline 1week, Psilocybin 1week
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| Contributor(s) |
Lundgaard Donovan L, Vilstrup Johansen J, Issazadeh-Navikas S, Jaberi E, Demant Hansen H, Moos Knudsen G |
| Citation(s) |
33288378 |
| |
| Submission date |
Apr 14, 2021 |
| Last update date |
Apr 20, 2021 |
| Contact name |
Gitte Moos Knudsen |
| E-mail(s) |
gmk@nru.dk
|
| Organization name |
Copenhagen University Hospital, Rigshospitalet
|
| Department |
Neurobiology Research Unit
|
| Street address |
9 Blegdamsvej
|
| City |
Copenhagen |
| ZIP/Postal code |
DK-2100 |
| Country |
Denmark |
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| Platforms (1) |
| GPL22475 |
Illumina HiSeq 4000 (Sus scrofa) |
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| Samples (23)
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| Relations |
| BioProject |
PRJNA721958 |
| SRA |
SRP314833 |
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