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Status |
Public on Apr 17, 2021 |
Title |
Whole transcriptome analysis of lung tissue from mice after thoraxtrauma with and without sEV biogenesis inhibitor GW4869 |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To assess trauma associated gene expression signatures in lungs after thorax trauma mediated by small extracellular vesicles (sEVs) total RNA was isolated from lung lysates of mice after experimental blunt chest trauma with/without intravenous injection of GW4869 (2µg/g body weight).
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Overall design |
RNA Profiling of trauma-associated gene expression impacted by inhibition of sEV biogenesis with GW4869 4hrs after experimenal thorax trauma in mice.
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Contributor(s) |
Seufferlein T, Eiseler T, Seibold T |
Citation missing |
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Submission date |
Apr 16, 2021 |
Last update date |
Apr 17, 2021 |
Contact name |
Tim Eiseler |
E-mail(s) |
tim.eiseler@uniklinik-ulm.de
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Organization name |
Ulm University
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Department |
Internal Medicine 1
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Street address |
Albert-Einstein Allee 23
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City |
Ulm |
ZIP/Postal code |
89081 |
Country |
Germany |
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Platforms (1) |
GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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Samples (20)
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This SubSeries is part of SuperSeries: |
GSE172212 |
Small extracellular vesicles propagate the inflammatory response after trauma. |
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Relations |
BioProject |
PRJNA722437 |
SRA |
SRP315098 |