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Series GSE172243 Query DataSets for GSE172243
Status Public on Apr 17, 2021
Title Reprogramming the spleen into a functioning “liver” in vivo II
Organism Mus musculus
Experiment type Expression profiling by array
Summary We restored liver function in the spleen by direct reprogramming splenic fibroblasts in situ and thereby transformed the spleen into a “liver” with sufficient physiological functions within a living animal.
 
Overall design The Gene Expression profiling of PBS-treated spleens (PBS) vs SiO2-remodelled spleens (SiO2), PBS as control; primary mouse SiO2-remodelled spleen fibroblasts (MF) vs hepatocyte-like cells (iHep) vs primary hepatocytes (PH), MF as control; SiO2-treated spleens (SiO2) vs SiO2-3TF-3C-treated spleen (hepatized spleens) vs normal liver tissues, SiO2 as control.Five cell/spleen samples were pooled according to individual groups.
 
Contributor(s) Dong L, Wang C, Zhang J
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 16, 2021
Last update date Apr 18, 2021
Contact name Chunyan Liu
E-mail(s) 18224538730@163.com
Organization name Nanjing University
Street address 163 Xianlin Avenue
City Nanjing
ZIP/Postal code 210093
Country China
 
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (3)
GSM5244683 Primary mouse SiO2-remodelled spleen fibroblasts (MF)
GSM5244684 Hepatocytes-like cells (iHep)
GSM5244685 Primary mouse hepatocytes (PH)
This SubSeries is part of SuperSeries:
GSE172245 Reprogramming the spleen into a functioning “liver” in vivo
Relations
BioProject PRJNA722515

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE172243_RAW.tar 6.4 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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