|
| Status |
Public on Mar 27, 2023 |
| Title |
Transcriptional profiline of murine and human T cell populations |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
T-regulatory-type-1 (TR1) cells comprise a phenotypically heterogenous but prevalent subset of Tregs that arise from unknown precursors in response to ill-defined cues. Here, we perform detailed transcriptional studies of autoantigen-specific TR1-like cell pools arising in response to peptide-major histocompatibility complex class II-coated nanoparticles (pMHCII-NPs) and compare them to other T cell populations to define their unique features.
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| |
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| Overall design |
Transcriptional characterization of autoantigen-specific TR1-like cell pools and other T cell populations in mice and human.
|
| Web link |
https://doi.org/10.1038/s41423-023-00989-z
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| |
|
| Contributor(s) |
Pere SV, Patricia SS, Garnica J |
| Citation(s) |
36973489 |
| Submission date |
Apr 30, 2021 |
| Last update date |
Mar 31, 2023 |
| Contact name |
Pere Santamaria |
| E-mail(s) |
pesantam@clinic.cat
|
| Organization name |
IDIBAPS
|
| Street address |
C/Rosselló 149-153
|
| City |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
| |
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| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (46)
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| Relations |
| BioProject |
PRJNA726582 |
| SRA |
SRP318056 |
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